K9 Advantix® II controls fleas, ticks and lice on dogs within one day of treatment and will continue to protect the dog from further flea, tick and lice infestations for at least four weeks. K9 Advantix® II also reduces biting by mosquitoes and stable flies; and kills mosquitoes. Active ingredients: imidacloprid, permethrin, pyriproxyfen. DO NOT USE ON CATS,KITTENS OR ANY OTHER ANIMALS AND IF CATS RESIDE IN THE HOUSEHOLD, SEPARATE FROM DOGS THAT HAVE HAD A RECENT APPLICATION FOR A MINIMUM OF 24 HOURS. READ ALL INSTRUCTIONS BEFORE USE.